Primary Breast Angiosarcoma: A Rare and Challenging Case Report

Primary angiosarcoma of the breast is a life-threatening and rare disease (0.04% of all breast cancers -BCs-). It has a variable and non-specific clinical, radiological and histological presentation; therefore its diagnosis is usually challenging. It predominantly affects young patients and there is often an excessive diagnostic delay, due to errors in the evaluation of imaging techniques and histological study. We report the case of a 56-year-old woman, with a history of bilateral breast reduction 10 years ago but with no personal history of BC or breast irradiation, who consulted for a rapidly growing breast mass. Initially, it was interpreted preoperatively as benign (haemorrhagic cyst); but its complete surgical removal confirmed the diagnosis of primary breast angiosarcoma. The tumor had a very aggressive behaviour, causing death 5 months after diagnosis.

Keywords: Breast angiosarcoma; Primary angiosarcoma; Breast cancer.